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Antibodies

RBP4 Monoclonal Antibody

Product Sizes
100 ul
£346.00
AN200017P-100UL
About this Product
SKU:
AN200017P
Additional Names:
RET,PRO,Retinol-binding protein,MCOPCB,RBP4,MCOPCB10,RDCCAS,RBP-4,RET4,PRBP,RBP,Retinol-binding protein 4,Plasma retinol-binding protein,Cleaved into Plasma retinol-binding protein,Plasma retinol-binding protein 1-181,Plasma retinol-binding protein 1-179,Plasma retinol-binding protein(1-176),PRO2222
Application:
IHC-Paraffin
Buffer:
PBS
translate.label.attr.clone:
A861
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
Retinol (also known as vitamin A) is unstable and insoluble in the aqueous solution. However, retinol becomes quite stable and soluble in plasma due to its tight interaction with retinol-binding protein 4 (RBP4), also known as plasma retinol-binding protein. A prototypic member of the lipocalin superfamily, RBP4 has a beta -barrel structure with a well-defined cavity. It is secreted from the liver, a process requiring the availability of retinol. RBP4 delivers retinol from the liver to the peripheral tissues. In plasma, the RBP4-retinol complex interacts with transthyretin (TTR), also known as thyroxine-binding protein and prealbumin. The retinol-RBP4-TTR complex prevents the loss of RBP4 by filtration through the kidney and increases the stability of the retinol-RBP4 complex. Defects in RBP4 cause retinol-binding protein deficiency, which affects night vision.
Host:
Mouse
Immunogen:
Recombinant Human RBP4 protein
Isotype:
IgG1
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody