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Antibodies

PE Anti-Human CD16 Antibody[B73.1]

Product Sizes
20 tests
£116.00
AN00950D-20TESTS
100 tests
£232.00
AN00950D-100TESTS
2 x 100 tests
£377.00
AN00950D-2X100TESTS
About this Product
SKU:
AN00950D
Additional Names:
FcG GammaRIII,IGFR3,FCG3,FCGR3,FCGRIII,Fc gamma receptor,Fc gamma receptor 3,CD16a
Application:
Flow Cytometry
Buffer:
PBS
translate.label.attr.clone:
B73.1
Clonality:
Monoclonal
Conjugate:
R-PE
Concentration:
5 ul/test
Extra Details:
CD16 is known as low affinity IgG receptor III (FcG GammaRIII). It is expressed as two distinct forms (CD16a and CD16b). CD16a (FcG GammaRIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. It is expressed on the surface of NK cells, activated monocytes, macrophages, a subset of T cells and placental trophoblasts in humans. CD16b (FcG GammaRIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein. Its extracellular domain is over 95% homologous to that of CD16a, and it is expressed specifically on neutrophils. CD16 binds aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC).
Host:
Mouse
Immunogen:
CD16
Isotype:
IgG1, kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody