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Antibodies

APC Anti-Mouse Ly-6A/E (Sca-1) Antibody[E13-161.7]

Product Sizes
50 tests
£73.00
AN00924E-50TESTS
100 tests
£91.00
AN00924E-100TESTS
2 x 100 tests
£124.00
AN00924E-2X100TESTS
About this Product
SKU:
AN00924E
Additional Names:
Sca-1
Application:
Flow Cytometry
Buffer:
PBS
translate.label.attr.clone:
E13-161.7
Clonality:
Monoclonal
Conjugate:
APC
Extra Details:
Ly-6A/E is an 18 kD member of the Ly-6 multigene family also known as Sca-1. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses. The E13-161.7 antibody has been reported to be useful for immunohistochemical staining of frozen sections, immunoprecipitation, flow cytometry, and complement-mediated cytotoxicity.
Host:
Rat
Immunogen:
Ly-6A/E
Isotype:
IgG2a, kappa
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody