Purified Anti-Human IL-9 Antibody[MH9D1]
Product Sizes
25 ug
£99.00
AN007840P-25UG
100 ug
£169.00
AN007840P-100UG
1 mg
£405.00
AN007840P-1MG
5 mg
£1515.00
AN007840P-5MG
25 mg
£5832.00
AN007840P-25MG
50 mg
£10187.00
AN007840P-50MG
100 mg
£14542.00
AN007840P-100MG
About this Product
- SKU:
- AN007840P
- Additional Names:
- Cytokine P;Interleukin;TCGF;IL9;HP40;IL-9;P40;Cytokine P40;Interleukin-9;P40 Cytokine;P40 T-cell and Mast Cell Growth Factor;T-cell Growth Factor P40;TCGF3;TCGFIII
- Application:
- Flow Cytometry
- Buffer:
- PBS, pH 7.2. Contains 0.05% proclin 300.
- translate.label.attr.clone:
- MH9D1
- Clonality:
- Monoclonal
- Concentration:
- >= 1 mg/ml
- Extra Details:
- Human IL-9 was originally identified as a cytokine found in the conditioned medium of a human T cell leukemia virus type I (HTLV-I) transformed T cell line that is mitogenic for the factor-dependent human megakaryoblastic leukemic cell line, M07e. The cDNA encoding this cytokine was subsequently isolated by functional expression cloning and found to be similar to the mouse T cell growth factor III/P40. This human cytokine and its murine homologue are now designated as human and mouse IL-9. Besides HTLV-I or -II transformed T cell lines, rhIL-9 is also produced by activated human PBLs. Human IL-9 was also reported to be expressed by primary and cultured Hodgkin and Reed-Sternberg (H-RS) cells derived from Hodgkin's disease patients, suggesting a possible role for rhIL-9 in the development of the pathophysiology of Hodgkin's disease.Human and murine IL-9 are also capable of enhancing in vitro survival of human T cell lines as well as synergizing with Epo to support erythroid colony formation in vitro. However, the mast cell enhancing activity associated with rmIL-9 has not yet been demonstrated in the human system and no human IL-9-dependent T cell clones have been identified.The gene for rhIL-9 has been mapped to human chromosome 5. As in the mouse system, the human IL-9 cDNA encodes a 144 amino acid residue precursor protein with an 18 amino acid signal peptide that is cleaved to form the mature cysteine-rich protein with a predicted molecular mass of 14 kDa. Human IL-9 contains four potential N-linked glycosylation sites and the native rhIL-9 is a highly glycosylated protein. Human and mouse IL-9 share 56% and 67% homology at the amino acid and nucleotide levels, respectively. Although murine IL-9 is active on human cells, human IL-9 is not active on mouse cells.
- Host:
- Mouse
- Immunogen:
- IL-9|Recombinant Human IL-9 protein
- Isotype:
- IgG1, kappa
- Purity:
- >98%
- Purification:
- protein a/g purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:NSVUWVi0
