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Antibodies

Caspase-9 Monoclonal Antibody

Product Sizes
25 ul
£134.00
AN007230L-25UL
100 ul
£291.00
AN007230L-100UL
About this Product
SKU:
AN007230L
Additional Names:
Apoptosis related cysteine peptidase,Apoptotic protease-activating factor 3,Caspase 9 apoptosis related cysteine peptidase,Caspase 9 Dominant Negative,Caspase 9c,Caspase-9 subunit p10,ICE LAP6,ICE like apoptotic protease 6,ICE-like apoptotic protease 6,protein phosphatase 1,regulatory subunit 56,RNCASP9,MCH,Apoptotic protease Mch,PPP1R,ICE-LAP,CASP9,APAF-3,APAF3,ICE-LAP6,MCH6,PPP1R56,caspase-9,Caspase 9,CASP-9,Apoptotic protease Mch-6,Apoptotic protease-activating factor 3 (APAF-3),ICE-like apoptotic protease 6 (ICE-LAP6)
Application:
Western Blot
Buffer:
PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
translate.label.attr.clone:
3B6
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
Host:
Mouse
Immunogen:
Recombinant Human Caspase-9 protein expressed by E.coli
Isotype:
IgG2a
Purification:
Protein A/G Purification
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody