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Antibodies

Ubiquitin Polyclonal Antibody

Product Sizes
25 ul
£134.00
AN007210L-25UL
100 ul
£291.00
AN007210L-100UL
About this Product
SKU:
AN007210L
Additional Names:
HEL-S-50,ubiquitin B,HEL-S,UBB,HEL-S-50,ubiquitin B,Polyubiquitin-B,Ubiquitin
Application:
Immunofluorescence, Immunohistochemistry
Buffer:
PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants.
Host:
Rabbit
Immunogen:
Recombinant Human Ubiquitin protein expressed by E.coli
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody