CCND1 Polyclonal Antibody
Product Sizes
25 ul
£134.00
AN006770L-25UL
100 ul
£291.00
AN006770L-100UL
About this Product
- SKU:
- AN006770L
- Additional Names:
- Cyl,PRAD,U21B,CCND,B cell leukemia,G1/S specific cyclin D,Cyclin D,BCL,BCL1,D11S287E,PRAD1,U21B31,CCND1,Cyclin D1,B cell leukemia 1,BCL 1,Cd1,Cyl 1,G1/S specific cyclin D1,BCL1,D11S287E,PRAD1,U21B31,CCND1,Cyclin D1,cyclin D1
- Application:
- Western Blot
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human CCND1 protein expressed by E.coli
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-ccnd1_polyclonal_antibody-an006770l
