S100A1 Polyclonal Antibody
Product Sizes
25 ul
£134.00
AN006750L-25UL
100 ul
£291.00
AN006750L-100UL
About this Product
- SKU:
- AN006750L
- Additional Names:
- S100A;S100A1;Bpb;NEF;Protein S100-A1;S100;S100 alpha;S100 beta;S100 calcium binding protein A1;S100 calcium binding protein B;S100 calcium-binding protein A1;S-100 protein alpha chain;S100 protein alpha polypeptide;S-100 protein subunit alpha;S100-alpha;S100B;S100beta;S100A1
- Application:
- Western Blot
- Buffer:
- PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Small calcium binding protein that plays important roles in several biological processes such as Ca2+ homeostasis, chondrocyte biology and cardiomyocyte regulation. In response to an increase in intracellular Ca2+ levels, binds calcium which triggers conformational changes .These changes allow interactions with specific target proteins and modulate their activity.Regulates a network in cardiomyocytes controlling sarcoplasmic reticulum Ca2+ cycling and mitochondrial function through interaction with the ryanodine receptors RYR1 and RYR2, sarcoplasmic reticulum Ca2+-ATPase/ATP2A2 and mitochondrial F1-ATPase. Facilitates diastolic Ca2+ dissociation and myofilament mechanics in order to improve relaxation during diastole.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human S100A1 protein expressed by E.coli
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-s100a1_polyclonal_antibody-an006750l
