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Antibodies

APC Anti-Rat CD172a Antibody[OX-41]

Product Sizes
50 tests
£78.00
AN00652E-50TESTS
100 tests
£99.00
AN00652E-100TESTS
2 x 100 tests
£138.00
AN00652E-2X100TESTS
About this Product
SKU:
AN00652E
Additional Names:
SIRPa,PTPNS1,BIT,MFR,p84,CD172 antigen-like family member A
Application:
Flow Cytometry
Buffer:
PBS
translate.label.attr.clone:
OX-41
Clonality:
Monoclonal
Conjugate:
APC
Concentration:
5 ul/test
Extra Details:
Rat CD172a, also known as a signal-regulatory protein (SIRP), is a 75-110 kD transmembrane glycoprotein involved in the receptor tyrosine kinase coupled signaling pathway. It belongs to the Ig superfamily primarily expressed on monocytes/macrophages, granulocytes, dendritic cells and neurons. CD172a serves as a substrate of activated receptor ttyrosine kinases (RTKs). The interaction of the CD172a intracellular domain with SHP-1 and SHP-2 displays negative signaling in the regulation of leukocyte adhesion and transmigration, T cell activation, macrophage fusion and phagocytosis. CD47 (IAP) is an extracellular ligand for CD172a.
Host:
Mouse
Immunogen:
CD172a
Isotype:
IgG2a, kappa
Reactivities:
Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody