Bcl-2 Polyclonal Antibody
Product Sizes
25 ul
£134.00
AN006000L-25UL
100 ul
£291.00
AN006000L-100UL
About this Product
- SKU:
- AN006000L
- Additional Names:
- PPP1R,PPP1R50,Bcl-2,Bcl2
- Application:
- Immunohistochemistry
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- BCL2 (BCL2 Apoptosis Regulator) is a Protein Coding gene. Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). Also acts as an inhibitor of autophagy: interacts with BECN1 and AMBRA1 during non-starvation conditions and inhibits their autophagy function. May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release.
- Host:
- Rabbit
- Immunogen:
- Recombinant Rat Bcl-2 protein expressed by E.coli
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-bcl_2_polyclonal_antibody-an006000l
