Ki67 Monoclonal Antibody
Product Sizes
25 ul
£134.00
AN005400L-25UL
100 ul
£291.00
AN005400L-100UL
About this Product
- SKU:
- AN005400L
- Additional Names:
- MIB;MKI;marker of proliferation Ki;Proliferation marker protein Ki;Antigen identified by monoclonal antibody Ki;PPP1R;MKI67;KIA;MIB-;MIB-1;PPP1R105;marker of proliferation Ki-67;Ki67;Antigen identified by monoclonal antibody Ki-67;Antigen Ki67;Antigen KI-67;Proliferation marker protein Ki-67;Antigen identified by monoclonal Ki 67;Antigen identified by monoclonal Ki-67;MIB 1;Proliferation related Ki 67 antigen;Protein phosphatase 1 regulatory subunit 105;RP11-380J17.2
- Application:
- Immunofluorescence, Immunohistochemistry
- Buffer:
- PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH 7.4
- translate.label.attr.clone:
- 3B7
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly. Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface. Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility. Binds DNA, with a preference for supercoiled DNA and AT-rich DNA. Does not contribute to the internal structure of mitotic chromosomes. May play a role in chromatin organization. It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable).
- Host:
- Mouse
- Immunogen:
- Recombinant human Ki67 protein expressed by E.coli
- Isotype:
- IgG1
- Purification:
- Protein A/G Purification
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-ki67_monoclonal_antibody-an005400l
