APC Anti-Mouse CD45R (B220) Antibody[RA3-6B2]
Product Sizes
50 tests
£81.00
AN00428E-50TESTS
100 tests
£104.00
AN00428E-100TESTS
2 x 100 tests
£147.00
AN00428E-2X100TESTS
About this Product
- SKU:
- AN00428E
- Additional Names:
- CD45R;B220
- Application:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- RA3-6B2
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Concentration:
- 5 ul/test
- Extra Details:
- CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker. CD19, however, may be more appropriate for B cell specificity.
- Host:
- Rat
- Immunogen:
- CD45R/B220
- Isotype:
- IgG2a, kappa
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-apc_anti_mouse_cd45r_(b220)_antibody[ra3_6b2]-an00428e
