APC Anti-Human/Mouse Integrin B Beta7 Antibody[FIB21]
Product Sizes
20 tests
£141.00
AN00423E-20TESTS
100 tests
£285.00
AN00423E-100TESTS
2 x 100 tests
£472.00
AN00423E-2X100TESTS
About this Product
- SKU:
- AN00423E
- Additional Names:
- B Beta7 Integrin;integrin B Betap;ITGB7
- Application:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- FIB21
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Concentration:
- 5 ul/test
- Extra Details:
- Integrin B Beta7 is a 130 kD glycoprotein also known as integin B Betap. It is a member of the Ig superfamily. In association with integrin A Alpha4 or A AlphaE chain, B Beta7 forms A Alpha4/B Beta7 or A AlphaE/B Beta7 heterodimer. A Alpha4/B Beta7 (CD49d/B Beta7, LPAM-1) is expressed on the majority of peripheral lymphocytes, on small subsets of thymocytes, and bone marrow progenitors. LPAM-1 binds to several ligands, VCAM-1, MAdCAM-1 and fibronectin, and is involved in lymphocyte adhesion and some hematopoietic progenitor cells migration. A AlphaE/B Beta7 (CD103/B Beta7,A AlphaIEL/B Beta7) is expressed on intestinal intraepithelial lymphocytes (IEL), dendritic epidermal T cells, T regulatory cells, a subset of CD8+ T cells in lymph nodes and lamina propria. CD103/B Beta7 complex is thought to play a role in lymphocyte retention via interaction with its ligand E-Cadherin.
- Host:
- Rat
- Immunogen:
- Integrin β7
- Isotype:
- IgG2b, kappa
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:mouse_integrin_β7_antibody[fib21]-an00423e
