Elab Fluor[R] Violet 450 Anti-Human HLA-DQ Antibody[1a3]
Product Sizes
20 tests
£116.00
AN00421Q-20TESTS
100 tests
£220.00
AN00421Q-100TESTS
2 x 100 tests
£305.00
AN00421Q-2X100TESTS
About this Product
- SKU:
- AN00421Q
- Additional Names:
- MHC class II DQ monomorphic antigen;MHC II
- Application:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- 1a3
- Clonality:
- Monoclonal
- Conjugate:
- Elab Fluor® Violet 450
- Concentration:
- 5 ul/test
- Extra Details:
- HLA-DQ is also known as MHC class II DQ monomorphic antigen. The major histocompatibility complex is composed of two heterodimeric glycoproteins (A Alpha and B Beta chains) with apparent molecular weights of 27 and 32 kD. In contrast to other MHC class II molecules, both polypeptide chains of HLA-DQ are polymorphic, with the A Alpha chain showing an extremely high degree of polymorphism. HLA-DQ is expressed on B cells in the peripheral blood, and weakly expressed on activated T cells and some monocytes. HLA-DQ is absent on hematopoietic progenitors, resting T cells, erythrocytes, and platelets. HLA-DQ is expressed after HLA-DR and HLA-DP in hematopoietic development. HLA-DQ presents peptide fragments mainly from degraded intravesicular and extracellular proteins to CD4+ T lymphocytes. Specific alleles of HLA-DQ have been linked to the pathogenesis of several autoimmune diseases (including diabetes), both as a susceptibility and resistance factor depending on the particular polymorphism.
- Host:
- Mouse
- Immunogen:
- HLA-DQ
- Isotype:
- IgG2a, kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-elab_fluor®_violet_450_anti_human_hla_dq_antibody[1a3]-an00421q
