APC Anti-Mouse CD122 Antibody[TM-Beta 1]
Product Sizes
25 ug
£117.00
AN00418UE-25UG
100 ug
£226.00
AN00418UE-100UG
About this Product
- SKU:
- AN00418UE
- Additional Names:
- IL-2 Receptor B Beta chain;IL-2RB Beta
- Application:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- TM-Beta 1
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Concentration:
- 0.2 mg/ml
- Extra Details:
- CD122 is a 70-75 kD IL-2 receptor B Beta chain also known as IL-2RB Beta, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2RB Beta chain can combine with either the common G Gamma subunit (G Gammac, CD132) alone or with the G Gammac subunit and the IL-2RA Alpha subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The TM-B Beta1 antibody does inhibit IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.
- Host:
- Rat
- Immunogen:
- CD122
- Isotype:
- IgG2b, kappa
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-apc_anti_mouse_cd122_antibody[tm_beta_1]-an00418ue
