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Antibodies

Purified Anti-Human ADAM10 Antibody[11G2]

Product Sizes
25 ug
£99.00
AN003550P-25UG
100 ug
£169.00
AN003550P-100UG
1 mg
£405.00
AN003550P-1MG
5 mg
£1515.00
AN003550P-5MG
25 mg
£5832.00
AN003550P-25MG
50 mg
£10187.00
AN003550P-50MG
100 mg
£14542.00
AN003550P-100MG
About this Product
SKU:
AN003550P
Additional Names:
CDw;ADAM;ADAM metallopeptidase domain;a disintegrin and metalloprotease domain;a disintegrin and metalloproteinase domain;disintegrin and metalloproteinase domain-containing protein;ADAM10;AD10;AD18;CD156c;CDw156;HsT18717;MADM;RAK;kuz;Kuzbanian;a disintegrin and metalloprotease domain 10;a disintegrin and metalloproteinase domain 10;ADAM metallopeptidase domain 10;CD156c antigen;disintegrin and metalloproteinase domain-containing protein 10;Kuzbanian protein homolog;Mammalian disintegrin-metalloprotease;ADAM metallopeptidase domain 10;CD156c;CDw156;HsT18717;kuz;MADM;AD 10;ADA10;ADAM 10;CD 156c;disintegrin and metalloproteinase domain containing protein 10;Drosophila;homolog of;HsT 18717;Mammalian disintegrin metalloprotease
Application:
Flow Cytometry
Buffer:
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
translate.label.attr.clone:
11G2
Clonality:
Monoclonal
Concentration:
>= 1 mg/ml
Extra Details:
ADAM10 (also known as Kuzbanian, mammalian disintegrin metalloprotease, myelin-associated metalloproteinase) is a member of the ADAM family that contains a disintegrin and metalloprotease-like domain . Like other membrane-anchored ADAMs, ADAM10 consists of the following domains, pro with a cysteine switch and furin cleavage sequence, catalytic with the zinc-binding site and Met-turn expected for reprolysins, disintegrin-like, cysteine-rich, EGF-like, transmembrane, and cytoplasmic. ADAM10 is highly conserved, with 97% amino acid identity between mouse, rat, bovine and human and 45% identity between mouse and Drosophila. The active enzyme processes notch, notch ligand delta, and amyloid protein precursor at the alpha site, playing an important role in neurogenesis . It also processes the 26 kDa membrane-anchored pro-tumor necrosis factor-alpha (TNF-alpha ) to the 17 kDa mature TNF-alpha. It cleaves myelin basic protein and type IV collagen. ADAM10 is widely expressed in tissues and resides both on the cell surface and in the cell.
Host:
Mouse
Immunogen:
ADAM10|Recombinant Human ADAM10 protein
Isotype:
IgG1, kappa
Purity:
>98%
Purification:
protein a/g purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody
  • Manufacturer's Data Sheet:yHhqmD
Human peripheral blood lymphocytes were stained with 0.2 ug Purified Anti-Human CD11a Antibody[TS1/22.1.1.13] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by FITC-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood lymphocytes were stained with 0.2 ug Purified Anti-Human CD18 Antibody[TS1/18.1.2.11] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by FITC-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood lymphocytes were stained with 0.2 ug Purified Anti-Human CD38 Antibody[HIT2] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by FITC-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood lymphocytes were stained with 0.2 ug Purified Anti-Human CD47 Antibody[CC2C6D4] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by FITC-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood granulocytes cell were stained with 0.2 ug Purified Anti-Human CD147 Antibody[HIM6] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.