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Antibodies

Purified Anti-Human CD180 Antibody[MHR73-11], Functional Grade

Product Sizes
100 ug
£85.00
AN003260-100UG
1 mg
£159.00
AN003260-1MG
5 mg
£446.00
AN003260-5MG
25 mg
£1369.00
AN003260-25MG
50 mg
£2028.00
AN003260-50MG
100 mg
£2895.00
AN003260-100MG
About this Product
SKU:
AN003260
Additional Names:
Ly78,LY64,RP105,CD180
Application:
Flow Cytometry
Buffer:
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
translate.label.attr.clone:
MHR73-11
Clonality:
Monoclonal
Concentration:
>= 1 mg/ml
Extra Details:
CD180, also known as RP105, is a 105 kD member of the toll-like receptor (TLR) family and is expressed on most B cells, monocytes/macrophages and dendritic cells. The TLR family's structural characteristics are critically involved in protein-protein signaling interactions leading to the activation of the innate immune system. Additionally, MD-1, a secretory protein, associates with CD180 (RP105) at the cell surface and this complex, in conjunction with TLR4, recognizes bacterial LPS. The human CD180 (RP105) gene maps to 5q12. The MHR73-11 antibody is able to activate B cells and to protect against irradiation- or dexamethasone-induced apoptosis. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
Host:
Mouse
Immunogen:
Recombinant Human CD180 protein
Isotype:
IgG1, kappa
Purification:
protein a/g purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody