PE/Elab Fluor[R] 594 Anti-Human CD46 Antibody[TRA-2-10]
Product Sizes
20 tests
£127.00
AN00324P-20TESTS
100 tests
£262.00
AN00324P-100TESTS
2 x 100 tests
£431.00
AN00324P-2X100TESTS
About this Product
- SKU:
- AN00324P
- Additional Names:
- Complement membrane cofactor protein;measles virus receptor;MCP
- Application:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- TRA-2-10
- Clonality:
- Monoclonal
- Conjugate:
- R-PE-Elab Fluor® 594
- Concentration:
- 5 ul/test
- Extra Details:
- CD46 is a transmembrane protein that is known as a complement membrane cofactor protein, MCP, and measles virus receptor. It is widely expressed on leukocytes, platelets, epithelial cells, and fibroblasts. Multiple isoforms of CD46 have been reported with molecular weights ranging from 45-75 kD. CD46 binds complement components C3b and C4b and has been reported to play a role in T cell regulation. In addition to the complement components, CD46 has been shown to interact with moesin, c-Src, tetraspanin 4, c-Yes, and integrin B Beta1. CD46 is also known to be a cellular receptor for human measles virus and human herpes virus-6 as well as other human pathogens, such as Streptococcus pyogenes. Defects in CD46 have been associated with hemolytic-uremic syndrome.
- Host:
- Mouse
- Immunogen:
- CD46
- Isotype:
- IgG1, kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:elab_fluor®_594_anti_human_cd46_antibody[tra_2_10]-an00324p
