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Antibodies

Purified Anti-Human CD85j Antibody[GHI/75], Functional Grade

Product Sizes
100 ug
£89.00
AN002890-100UG
1 mg
£171.00
AN002890-1MG
5 mg
£490.00
AN002890-5MG
25 mg
£1515.00
AN002890-25MG
50 mg
£2247.00
AN002890-50MG
100 mg
£3211.00
AN002890-100MG
About this Product
SKU:
AN002890
Additional Names:
LILRB,ILT,LIR,MIR,LILRB1,CD85J,ILT-2,ILT2,LIR-1,LIR1,MIR-7,MIR7,PIR-B,PIRB, ILT2, LILRB1,CD85,CD85 antigen,CD85 antigen like family member J,CD85 antigen-like family member J,CD85j antigen,Ig like transcript 2,ILT 2,immunoglobulin like transcript 2,Immunoglobulin-like transcript 2,leukocyte Ig like receptor 1,leukocyte immunoglobulin like receptor,Leukocyte immunoglobulin like receptor 1,leukocyte immunoglobulin like receptor subfamily B member 1,Leukocyte immunoglobulin like receptor subfamily B member 1 precursor,leukocyte immunoglobulin like receptor subfamily B member 1 soluble isoform,leukocyte immunoglobulin-like receptor,Leukocyte immunoglobulin-like receptor 1,Leukocyte immunoglobulin-like receptor subfamily B member 1,leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform,LIR 1,LIRB1,member 1,MIR 7,Monocyte/macrophage immunoglobulin like receptor 7,Monocyte/macrophage immunoglobulin-like receptor 7,PIR B,subfamily B,subfamily B (with TM and ITIM domains)
Application:
Cell-based/Functional Assay, Flow Cytometry
Buffer:
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
translate.label.attr.clone:
GHI/75
Clonality:
Monoclonal
Concentration:
>= 1 mg/ml
Extra Details:
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
Host:
Mouse
Immunogen:
Recombinant Human CD85j protein
Isotype:
IgG2b, kappa
Purity:
>98%
Purification:
protein a/g purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody
Human peripheral blood lymphocytes were stained with 0.2 ug Purified Anti-Human CD85j Antibody[GHI/75], Functional Grade (Right) and 0.2 ug Mouse IgG2b, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
THP-1 were stained with 0.2 ug Purified Anti-Human CD105 Antibody[SN6h] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood lymphocytes were stained with 0.2 ug Purified Anti-Human CD25 Antibody[CHI621] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody, then anti-Human CD4 PE-conjugated Monoclonal Antibody.
Human peripheral blood lymphocytes were stained with 0.2 ug Purified Anti-Human TCRCB Beta1 Antibody[JOVI.1] (Right) and 0.2 ug Mouse IgG2a, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood were stained with 0.2 ug Purified Anti-Human CD45 Antibody[QA17A19] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by FITC-conjugated Goat Anti-Mouse IgG Secondary Antibody.