Sphingosine 1-Phosphate Antibody
Product Sizes
10 ug
£265.00
ECH-Z-P300-10UG
50 ug
£597.00
ECH-Z-P300-50UG
250 ug
£2027.00
ECH-Z-P300-250UG
About this Product
- SKU:
- ECH-Z-P300
- Application:
- ELISA, Immunocytochemistry, Immunohistochemistry
- Clonality:
- Monoclonal
- Extra Details:
- Purified Anti-Sphingosine 1-Phosphate (S1P) monoclonal antibody. \nSubclass: IgGk1 \nSource: Mouse \nApplications: ELISA, Immunohistochemistry, Immunocytochemistry \n \n \n \nProduct Background: Sphingosine 1-Phosphate (S1P) is a key component of the sphingolipid signaling cascade. S1P initiates a proliferative, pro-angiogenic and anti-apoptotic sequence of events contributing to cancer progression. Recently, scientific literature has suggested that S1P is a potent tumorigenic growth factor that is likely released from tumor cells and that S1P may be a novel biomarker for early stage cancer detection. Sphingosine kinase has also been shown to be up-regulated in a variety of cancer types. S1P antibody (LT1002) was originally developed and patented at Lpath Therapeutics. \nStorage \nAntibody is stable for up to 1 year at -20 °C. Antibody is stable for 60 days at 4°C. Avoid repeated freeze/thaw cycles. \nReferences \n1) Visentin B, Reynolds G, Sabbadini R. (2012) Immunohistochemical detection of sphingosine-1-phosphate and sphingosine kinase-1 in human tissue samples. Methods Mol Biol. 874:55-67. \n2) O'Brien N, Jones ST, Williams DG, Cunningham HB, Moreno K, Visentin B, et al. (2009) Production and characterization of monoclonal anti-sphingosine-1-phosphate antibodies. J Lipid Res.;50(11):2245-57. \n3) Swaney JS, Moreno KM, Gentile AM, Sabbadini RA, Stoller GL. (2008) Sphingosine-1-phosphate (S1P) is a novel fibrotic mediator in the eye. Exp Eye Res.;87(4):367-75. \n \nBulk discounts available, please email echelon@echelon-inc.com for information. \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
- Immunogen:
- sphingosine 1-phosphate
- Isotype:
- IgG1, kappa
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Echelon Biosciences
- Type:
- Antibody: Monoclonal Antibody
