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Antibodies

Lysophosphatidic Acid Antibody (504B3)

Product Sizes
10 ug
£265.00
ECH-Z-P200-10UG
50 ug
£597.00
ECH-Z-P200-50UG
250 ug
£2027.00
ECH-Z-P200-250UG
About this Product
SKU:
ECH-Z-P200
Application:
ELISA, Immunocytochemistry, Immunohistochemistry
Clonality:
Monoclonal
Extra Details:
Purified Anti-Lysophosphatidic Acid (LPA) monoclonal antibody. \nSubclass: IgGk1 \nSource: Mouse \nApplications: ELISA, Immunohistochemistry, Immunocytochemistry \n \n \n \nProduct Background: Lysophosphatidic Acid (LPA) is a serum-derived phospholipid involved in diverse ceullular processes such as cell proliferation, chemotaxis, platelet aggregation, wound healing, angiogensis, tumor invasion, and smooth muscle contraction. Recent research indicates LPA may play a significant role in the pathophysiology of cancer and may be used as a biomarker for ovarian cancer. The Lysophosphatidic Acid Antibody (504B3) was originally developed and patented at Lpath Therapeutics. \nStorage \nAntibody is stable for up to 1 year at -20 °C. Antibody is stable for 60 days at 4°C. Avoid repeated freeze/thaw cycles. \nReferences \n1) J. Cheng, S. Sahani, T.J. Hausrat, et al. (2016) "Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling" Neuron, 92(1); 126-142. doi: doi:10.1016/j.neuron.2016.08.035 \n2) M. Balood, H. Zahednasab, et al. (2014) "Elevated serum levels of lysophosphatidic acid in patients with multiple sclerosis" Hum. Immunol. 75(5); 411-413, doi: 10.1016/j.humimm.2014.02.021 \n3) Y. Goldshmit, R. Matteo, et al. (2012) "Blockage of lysophosphatidic acid signaling improves spinal cord injury outcomes." Am. J. Pathol. , 181(3): 978-992, doi: 10.1016/j.ajpath.2012.06.007 \n \nBulk discounts available, please email echelon@echelon-inc.com for information. \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
Immunogen:
lysophosphatidic acid
Isotype:
IgG1, kappa
Shipping Conditions:
Dry Ice
Storage Conditions:
-20[o]C
Supplier:
Echelon Biosciences
Type:
Antibody: Monoclonal Antibody