Purified Anti-PtdIns(4)P IgM
Product Sizes
10 ug
ECH-Z-P004-10UG
50 ug
ECH-Z-P004-50UG
250 ug
ECH-Z-P004-250UG
About this Product
- SKU:
- ECH-Z-P004
- Clonality:
- Monoclonal
- Extra Details:
- Purified Anti-PtdIns(4)P monoclonal antibody.Subclass: IgMSource: MouseApplications: ELISA Immunofluorescence Fluorescence Polarization Protein-Lipid Overlay (PIP Strip)Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4-phosphate (PI(4)P) is the biosynthetic precursor to PI(4 5)P2 and has an important roles in regulating sphingomyelin and glycosphingolipid metabolism and membrane trafficking at the exit of the Golgi complex. Powered by Bioz See more details on BiozFeatured in Publications1) Weber S. S. C. Ragaz et al. (2006). "Legionella pneumophila exploits PI(4)P to anchor secreted effector proteins to the replicative vacuole." PLoS Pathog 2(5): e46.2) Blagoveshchenskaya A. F. Y. Cheong et al. (2008). "Integration of Golgi trafficking and growth factor signaling by the lipid phosphatase SAC1." J Cell Biol 180(4): 803-12.3) Cheong F. Y. V. Sharma et al. (2010). "Spatial Regulation of Golgi Phosphatidylinositol-4-Phosphate is Required for Enzyme Localization and Glycosylation Fidelity." Traffic 11(9): 1180-1190.4) Bojjireddy N. J. Botyanszki et al. "Pharmacological and Genetic Targeting of the PI4KA Enzyme Reveals Its Important Role in Maintaining Plasma Membrane Phosphatidylinositol 4-Phosphate and Phosphatidylinositol 4 5-Bisphosphate Levels." Journal of Biological Chemistry 289(9): 6120-6132.Product keywords: PtdIns(4)P anti-PI(4)P PI4P IgM
- Immunogen:
- ptdins(4)p
- Isotype:
- IgM
- Purification:
- Purified
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Echelon Biosciences
- Type:
- Antibody: Monoclonal Antibody