Anti-PtdIns(3,4,5)P3 IgM HRP
Product Sizes
10 ug
£450.00
ECH-Z-H345-10UG
50 ug
£787.00
ECH-Z-H345-50UG
250 ug
£1964.00
ECH-Z-H345-250UG
About this Product
- SKU:
- ECH-Z-H345
- Application:
- ELISA, Immunofluorescence
- Clonality:
- Monoclonal
- Extra Details:
- Purified Anti-PtdIns(3,4,5)P3 monoclonal antibody conjugated with horseradish peroxidase. \nSubclass: IgM \nSource: Mouse \nApplications: ELISA, Immunofluorescence \n \n \n \nProduct Background:Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4,5-trisphosphate (PIP3), formed from PI(4,5)P2 though phosphorylation by PI 3-kinase, activates numerous signaling pathways resulting in cell proliferation, growth, survival, glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4,5)P2 and SHIP to PI(3,4)P2. \nStorage \n2-8 °C for up to 30 days, -20 °C for greater than 30 days. Do not freeze thaw multiple times. \nFeatured in Publications \n1) Garcia-San Frutos, M., T. Fernandez-Agullo, et al. (2007). "Impaired central insulin response in aged Wistar rats: role of adiposity." Endocrinology 148(11): 5238-47. \n \nProduct keywords: PIP3, PI(3,4,5)P3, PtdIns(3,4,5)P3, IgM, anti-PIP3 \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
- Immunogen:
- Anti-PtdIns(3,4,5)P3 IgM HRP
- Shipping Conditions:
- Blue Ice
- Supplier:
- Echelon Biosciences
- Type:
- Antibody: Monoclonal Antibody
