Biotinylated Anti-PtdIns(4,5)P2 IgM
Product Sizes
10 ug
£515.00
ECH-Z-B045-10UG
50 ug
£867.00
ECH-Z-B045-50UG
250 ug
£2285.00
ECH-Z-B045-250UG
About this Product
- SKU:
- ECH-Z-B045
- Application:
- ELISA, Flow Cytometry, Immunofluorescence
- Clonality:
- Monoclonal
- Conjugate:
- Biotin
- Extra Details:
- Purified Anti-PtdIns(4,5)P2 monoclonal antibody conjugated with biotin. \nSubclass: IgM \nSource: Mouse \nApplications: ELISA, Immunofluorescence, Protein-Lipid Overlay (PIP Strip), Flow Cytometry \n \n \n \nProduct Background: Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4,5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions, PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues. It is also a substrate for class I phosphoinositide 3-kinase (PI3-K) forming PIP3. \nStorage \n2-8 °C for up to 30 days, -20 °C for greater than 30 days. Do not freeze thaw multiple times \nFeatured in Publications \n1) Hoek, K. L., P. Antony, et al. (2006). "Transitional B cell fate is associated with developmental stage-specific regulation of diacylglycerol and calcium signaling upon B cell receptor engagement." J Immunol 177(8): 5405-13. \n2) Antony, P., K. Hoek, et al. (2007). "Micro-scale flow cytometry-based and biochemical analysis of lipid signaling in primary B cell subpopulations." Biol Proced Online 9: 73-83. \n3) Marquez, M. G., C. Fernandez-Tome Mdel, et al. (2009). "Bradykinin induces formation of vesicle-like structures containing vinculin and PtdIns(4,5)P2 in renal papillary collecting duct cells." Am J Physiol Renal Physiol 297(5): F1181-91. \n \nProduct keywords: PIP2, PI(4,5)P2, PtdIns(4,5)P2, IgM, anti-PIP2 \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
- Immunogen:
- Biotinylated Anti-PtdIns(4,5)P2 IgM
- Isotype:
- IgM
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Echelon Biosciences
- Type:
- Antibody: Monoclonal Antibody
