Anti-PtdIns(4,5)P2 IgM In Ascites
Product Sizes
100 ug
£362.00
ECH-Z-A045-100UG
200 ug
£502.00
ECH-Z-A045-200UG
500 ug
£896.00
ECH-Z-A045-500UG
About this Product
- SKU:
- ECH-Z-A045
- Application:
- ELISA, Immunofluorescence
- Clonality:
- Monoclonal
- Extra Details:
- Anti-PtdIns(4,5)P2 monoclonal antibody in ascites. \nSubclass: IgM \nSource: Mouse \nApplications: ELISA, Immunofluorescence, Protein-Lipid Overlay (PIP Strip) \n \n \n \nProduct Background: Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4,5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions, PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues. It is also a substrate for class I phosphoinositide 3-kinase (PI3-K) forming PIP3. \nStorage \n \n 2-8 °C for up to 30 days, -20 °C for greater than 30 days. Do not freeze thaw multiple times \n \nFeatured in Publications \n1) Terebiznik, M. R., O. V. Vieira, et al. (2002). "Elimination of host cell PtdIns(4,5)P(2) by bacterial SigD promotes membrane fission during invasion by Salmonella." Nat Cell Biol 4(10): 766-73. \n2) Hirono, M., C. S. Denis, et al. (2004). "Hair cells require phosphatidylinositol 4,5-bisphosphate for mechanical transduction and adaptation." Neuron 44(2): 309-20. \n3) Leloup, L., H. Shao, et al. (2010). "m-calpain Activation Is Regulated by Its Membrane Localization and by Its Binding to Phosphatidylinositol 4,5-Bisphosphate." Journal of Biological Chemistry 285(43): 33549-33566. \n \nProduct keywords: PIP2, PI(4,5)P2, PtdIns(4,5)P2, IgM, anti-PIP2 \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
- Format:
- Ascites
- Host:
- Mouse
- Immunogen:
- Anti-PtdIns(4,5)P2 IgM In Ascites
- Isotype:
- IgM
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Echelon Biosciences
- Type:
- Antibody: Monoclonal Antibody
