S1P Beads
Product Sizes
100 ul
£288.00
ECH-S-6110-100UL
1 ml
£1179.00
ECH-S-6110-1ML
About this Product
- SKU:
- ECH-S-6110
- Extra Details:
- S1P Beads are composed of agarose with 10 nanomoles of bound Sphingosine 1-Phosphate (S1P) per mL of beads, enough for several protein binding experiments. Each 1 mL order of S1P Beads includes a small amount of control beads. Larger quantities of Control Beads are also available for purchase. \n \n \n \nStorage \n4 °C - do not freeze< \nApplications \nS1P beads are designed for use in protein pull-down experiments to identify and characterize S1P binding proteins. Possible applications include the isolation of lipid-binding proteins present in a cell lysate or in a mixture of in vitro translated peptides, for separation by SDS-PAGE and further analysis. \nFeatured in Publications \n1) N. C. Hait, J. Allegood, et al. (2009) "Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate" Science 325(5945), 1254-7 \n2) G. M. Strub, M. Paillard, et al. (2011) "Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration" The FASEB Journal 25(2), 600-612 10.1096/fj.10-167502 \n3) E.-S. Park, S. Choi, et al. (2015) "Tumor Necrosis Factor (TNF) Receptor-associated Factor (TRAF)-interacting Protein (TRIP) Negatively Regulates the TRAF2 Ubiquitin-dependent Pathway by Suppressing the TRAF2-Sphingosine 1-Phosphate (S1P) Interaction" J. Biol. Chem. 290(15), 9660-9673 10.1074/jbc.M114.609685 \n4) Parham, K. A., et al. (2015). "Sphingosine 1-phosphate is a ligand for peroxisome proliferator-activated receptor-G Gamma that regulates neoangiogenesis." The FASEB Journal 29(9): 3638-3653. \n \nBeing bio-reactive blog: "Lipid-Ligand interaction tools: lipids are not scary intermediates anymore" \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Echelon Biosciences
- Type:
- Microspheres: Protein Coated
