S1P Lyase Fluorogenic Substrate
Product Sizes
1 mg
£656.00
ECH-S-200U-1MG
5 mg
£2406.00
ECH-S-200U-5MG
10 mg
£4499.00
ECH-S-200U-10MG
About this Product
- SKU:
- ECH-S-200U
- Extra Details:
- S1P Lyase Fluorogenic Substrate is designed for monitoring S1PL activity by releasing fluorescent 7-hydroxycoumarin in the presence of active enzyme. \n \nSphingosine-1-phosphate lyase (S1PL) is an enzyme that breaks sphingosine-1-phosphate into hexadecenal and phosphoethanolamine. S1PL has been proposed as a target for autoimmune disorder treatment and in cancer therapy. \n \n \n \nStorage \n-20°C or below. \nReferences \n1. Billich, A., et al. (2013). "Partial deficiency of sphingosine-1-phosphate lyase confers protection in experimental autoimmune encephalomyelitis." PLoS One 8(3): e59630. \n2. Engel, N., et al. (2012). "Metabolic profiling reveals sphingosine-1-phosphate kinase 2 and lyase as key targets of (phyto-) estrogen action in the breast cancer cell line MCF-7 and not in MCF-12A." PLoS One 7(10): e47833. \n3. Bedia, C., et al. (2009). "Synthesis of a fluorogenic analogue of sphingosine-1-phosphate and its use to determine sphingosine-1-phosphate lyase activity." Chembiochem 10(5): 820-2. \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
- Format:
- Fluorometric
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Echelon Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
