Propargyl-geraniol
Product Sizes
5 mg
£273.00
ECH-S-0110-5MG
10 mg
£429.00
ECH-S-0110-10MG
About this Product
- SKU:
- ECH-S-0110
- Extra Details:
- Propargyl-geraniol ((E,E)-3,7-Dimethyl-8-(2-propargyloxy)-2,6-octadien-1-ol) is an alkyne-modified isoprenoid that acts as a chemical reporter of protein prenylation via "Click" chemistry. \n \nThe alkyne-modified isoprenoids were developed by the Distefano group at the University of Minnesota as chemical reporters of protein prenylation. The isoprenoids readily penetrate mammalian cells and are used as substrates by prenyltransferases. The pendant alkyne can be derivatized with an azide-containing tag, such as a fluorophore or biotin, via a Cu(I) catalyzed "Click" reaction allowing the prenylated proteins to be identified and quantified. \n \n \n \nStorage \n-20 °C or below \nReferences \n1) A.J. DeGraw, et al. "Evaluation of alkyne-modified isoprenoids as chemical reportersof protein prenylation" (2010) Chem. Biol. Drug Des. 76, 460-47, doi: 10.1111/j.1747-0285.2010.01037.x \n2) B.P. Duckworth, et al "Selective Labeling of Proteins by Using Protein Farnesyltransferase" (2007) ChemBioChem 8, 98-105. DOI: 10.1002/cbic.200600340 \n \nKeywords: (E,E)-3,7-Dimethyl-8-(2-propargyloxy)-2,6-octadien-1-ol \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Echelon Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Substrates
