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Proteins and Peptides

PI4-Kinase II beta (PI4KIIb), active

Product Sizes
5 ug
£510.00
ECH-P22-10G-5UG
10 ug
£685.00
ECH-P22-10G-10UG
About this Product
SKU:
ECH-P22-10G
Application:
Detection/Quantitation, Western Blot
Extra Details:
Full-length recombinant human PI4KIIB was co-expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. Enzyme obtained from SignalChem. \n \nMolecular weight: ~84 kDa \nSequence: Full length \nSpecies: Human \nTag: GST tag \nPurity: >90 % (see TDS for lot specific information) \nSpecific Activity: >30 nmol/min/mg (see TDS for lot specific information) \nExpression System: Sf9 insect cells using baculovirus \nGenebank Number: NM_018323 \nApplications: PI 4-Kinase assay , western blot. \nFormulation: Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. \nStorage and stability: Store product at -70C. Stable up to one year \n \n \n \nProduct Description: \n \nPI4KIIB is a member of the phosphatidylinositol 4-kinase family (PI4K) that phosphorylate phosphatidylinositol to generate phosphatidylinositol 4-phosphate which are immediate precursor of several important signaling and scaffolding molecules. PI4KIIB is primarily a cytosolic PI4K that is recruited to membranes where it stimulates phosphatidylinositol 4,5-bisphosphate syntheses. PI4KIIB uses phosphatidylinositol as their primary substrate and has no activity on phosphatidylinositol monophosphates. PI4KIIB is a restricted minor histocompatibility antigen in patients that had been successfully treated with donor lymphocyte infusions for relapsed chronic myeloid leukemia after allogeneic stem cell transplantation. \n \n, Echelon
Shipping Conditions:
Dry Ice
Storage Conditions:
-70[o]C
Supplier:
Echelon Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes