NeoBeads - PIP Purification System
Product Sizes
20 mg
£355.00
ECH-P-B999-20MG
About this Product
- SKU:
- ECH-P-B999
- Extra Details:
- The NeoBeads - PIP Purification System is useful in biological and chemical applications for purification of lipids. Each milligram of beads will bind at least 1 nmole phosphoinositide. The NeoBeads - PIP Purification System allows for selective purification/immobilization of phosphoinositides from biological samples. Phosphoinositides can be recovered from the beads using fresh 2 M aqueous triethylamine bicarbonate, chloroform, methanol (3:2:6; v/v). See the Technical Data Sheet for protocol and further details. \n \n- Quick purification of Phosphoinositides from biological samples \n- High Binding capacity: greater than 1 nanomole phosphoinositide per mg bead \n- Reproducable batches: low lot-to-lot variability \n- Cited in multiple scientific papers over 20+ years describing uses, techniques and protocols. \n- First commercially available solid-supported neomycin \nReferences \n1) A. Grey, H. Olsson, I.H. Batty, L. Priganica, C.P. Downes: Nonradioactive methods for the assay of phosphoinositide 3-kinases and phosphoinositide phosphates and selective detection of signaling lipids in cell and tissue extracts. Analytical Biochemistry 313 234-245 (2003). \n2)Sbrissa, D., Ikonomov, O. C., Deeb, R., and Shisheva, A., Phosphatidylinositol 5-phosphate biosynthesis is linked to PIKfyve and is involved in osmotic response pathway in mammalian cells, J Biol Chem, 277, 47276 (2002). \n3) Sierra Potchanant, E. A., et al. (2016). "INPP5E preserves genomic stability through regulation of mitosis." Mol Cell Biol 37: e00500-00516. \n \nKeywords: phosphoinositide, purification, PIP, beads, resin \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Echelon Biosciences
- Type:
- Microspheres: Protein Coated
