PI(5)P diC4
Product Sizes
100 ug
£310.00
ECH-P-5004-100UG
500 ug
£700.00
ECH-P-5004-500UG
1 mg
£1118.00
ECH-P-5004-1MG
About this Product
- SKU:
- ECH-P-5004
- Extra Details:
- Phosphatidylinositol 5-phosphate diC4 (PI(5)P diC4) is a synthetic, purified dibutanoyl PI(5)P. \n \nPhosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 5-phosphate (PI(5)P) is a rare lipid found in the nucleus that can bind the PHD finger of the nuclear adapter protein ING2. PI(5)P is phosphorylated to PI(4,5)P2 by Type II PIP kinases. \n \n \n \nStorage \n-20 °C \nFeatyred in Publications \n1) Guo, J., M. R. Wenk, et al. (2003). "Phosphatidylinositol 4-kinase type IIalpha is responsible for the phosphatidylinositol 4-kinase activity associated with synaptic vesicles." Proc Natl Acad Sci U S A 100(7): 3995-4000. \n2) Pendaries, C., H. Tronchere, et al. (2006). "PtdIns5P activates the host cell PI3-kinase/Akt pathway during Shigella flexneri infection." Embo J 25(5): 1024-34. \n3) Ramel, D., F. Lagarrigue, et al. (2011). "Shigella flexneri Infection Generates the Lipid PI5P to Alter Endocytosis and Prevent Termination of EGFR Signaling." Sci. Signal. 4(191): ra61-. \n4) Boal, F. d. r., A. Puhar, et al. (2016). "PI5P Triggers ICAM-1 Degradation in Shigella Infected Cells, Thus Dampening Immune Cell Recruitment." Cell Reports., doi:10.1016/j.celrep.2015.12.079 \n \nAlternate Names: D-myo-Phosphatidylinositol 5-phosphate, Dibutanoyl Phosphatidylinositol 5-phosphate, PtdIns(5)P C4, PI(5)P C4, or PI5P \n \nBulk discounts available, please email echelon@echelon-inc.com for information. \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Echelon Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
