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Proteins and Peptides

GroPI(4,5)P2

Product Sizes
100 ug
£310.00
ECH-P-4500-100UG
500 ug
£700.00
ECH-P-4500-500UG
1 mg
£1118.00
ECH-P-4500-1MG
About this Product
SKU:
ECH-P-4500
Extra Details:
Glycerophosphoinositol 4,5-diphosphate (GroPI(4,5)P2) is a synthetic, purified PI(4,5)P2 without acyl chains at the 1- and 2-positions of the glycerol. \n \nPhosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4,5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions, PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues and is also a substrate for class I phosphoinositide 3-kinase (PI3-K). \n \n \n \nStorage \n-20 °C \nFeatured in Publications \n1) Zizza, P., C. Iurisci, et al. (2012). "Phospholipase A2 IValpha regulates phagocytosis independent of its enzymatic activity." J Biol Chem 287(20): 16849-16859. \n \nProduct Keywords: Glycerophosphatidylinositol 4,5-bisphosphate, GroPtdIns(4,5)P2, GroPI(4,5)P2, or GroPI45P2 \n \nBulk discounts available, please email echelon@echelon-inc.com for information. \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
Shipping Conditions:
Dry Ice
Storage Conditions:
Please refer to datasheet
Supplier:
Echelon Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules