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Proteins and Peptides

PI(3,4,5)P3 18:0/20:4

Product Sizes
100 ug
£352.00
ECH-P-3924-100UG
500 ug
£1141.00
ECH-P-3924-500UG
1 mg
£1853.00
ECH-P-3924-1MG
About this Product
SKU:
ECH-P-3924
Extra Details:
PI(3,4,5)P3 (Phosphatidylinositol 3,4,5-trisphosphate) 18:0/20:4 is a synthetic, purified PI(3,4,5)P3 with stearoyl and arachidonoyl acyl groups. \n \nPhosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4,5-trisphosphate (PIP3), formed from PI(4,5)P2 though phosphorylation by PI 3-kinase, activates numerous signaling pathways resulting in cell proliferation, growth, survival, glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4,5)P2 and SHIP to PI(3,4)P2. \n \n \n \nProduct Keywords: 1-Stearoyl-2-arachidonoyl-phosphatidylinositol 3,4,5-trisphosphate, PtdIns(3,4,5)P3 (18:0/20:4), PI(3,4,5)P3 (18:0/20:4), or PIP3 \n \nBulk discounts available, please email echelon@echelon-inc.com for information. \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
Shipping Conditions:
Dry Ice
Storage Conditions:
Please refer to datasheet
Supplier:
Echelon Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules