PI(3,4)P2 diC16 (ammonium salt)
Product Sizes
100 ug
£185.00
ECH-P-3416A-100UG
500 ug
£400.00
ECH-P-3416A-500UG
1 mg
£614.00
ECH-P-3416A-1MG
About this Product
- SKU:
- ECH-P-3416A
- Extra Details:
- PI(3,4)P2 diC16 (Phosphatidylinositol 3,4-bisphosphate diC16) ammonium salt is a synthetic dipalmitoyl PI(3,4)P2. \n \nPhosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4-bisphosphate (PI(3,4)P2) is produced in stimulated cells by the action of phosphatidylinositol 3-kinases (PI3Ks) and/or lipid phosphatases (SHIP, TPTE, etc.). PI(3,4)P2 binds the pleckstrin homology (PH)-domain of AKT/PKB leading to cell survival and it also has an important role in podosome formation near focal adhesions. \nSolubility \n70:28:4 CHCl3:MeOH:H2O, 0.5 mg/ml \nFeatured in Publications \n1) Dowler, S., R. A. Currie, et al. (1999). "DAPP1: a dual adaptor for phosphotyrosine and 3-phosphoinositides." Biochem J 342(Pt 1): 7-12. \n2) Karathanassis, D., R. V. Stahelin, et al. (2002). "Binding of the PX domain of p47(phox) to phosphatidylinositol 3,4- bisphosphate and phosphatidic acid is masked by an intramolecular interaction." Embo J 21(19): 5057-68. \n3) Stampoulis, P., T. Ueda, et al. (2012). "Atypical membrane-embedded PI(3,4)P2 binding site on p47phox PX domain revealed by NMR." J Biol Chem(287): 17848-17859. \n \nProduct Keywords: Dipalmitoyl Phosphatidylinositol 3,4-bisphosphate, PtdIns(3,4)P2 C16, PI(3,4)P2 C16, or PI34P2. \n \nBulk discounts available, please email echelon@echelon-inc.com for details. \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Echelon Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
