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Proteins and Peptides

PI(3,4)P2 diC4

Product Sizes
100 ug
£316.00
ECH-P-3404-100UG
250 ug
£499.00
ECH-P-3404-250UG
500 ug
£783.00
ECH-P-3404-500UG
1 mg
£1310.00
ECH-P-3404-1MG
About this Product
SKU:
ECH-P-3404
Extra Details:
PI(3,4)P2 diC4 (Phosphatidylinositol 3,4-bisphosphate diC4) is a synthetic, purified dibutanoyl PI(3,4)P2. \n \nPhosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4-bisphosphate (PI(3,4)P2) is produced in stimulated cells by the action of phosphatidylinositol 3-kinases (PI3Ks) and/or lipid phosphatases (SHIP, TPTE, etc.). PI(3,4)P2 binds the pleckstrin homology (PH)-domain of AKT/PKB leading to cell survival and it also has an important role in podosome formation near focal adhesions. \n \n \n \nFeatured in Publications \n1. Fernandes, F., et al. (2011). "Phosphoinositides direct equine infectious anemia virus gag trafficking and release." Traffic 12(4): 438-451. \n2. Stampoulis, P., T. Ueda, et al. (2012). "Atypical membrane-embedded PI(3,4)P2 binding site on p47phox PX domain revealed by NMR." J Biol Chem(287): 17848-17859. \n \nProduct Keywords: Dibutanoyl Phosphatidylinositol 3,4-bisphosphate, PtdIns(3,4)P2 C4, PI(3,4)P2 C4, or PI34P2. \n \nBulk discounts available, please email echelon@echelon-inc.com for details. \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
Shipping Conditions:
Dry Ice
Storage Conditions:
Please refer to datasheet
Supplier:
Echelon Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules