XY-17 (LPA3 Agonist)
Product Sizes
500 ug
£621.00
ECH-L-9118-500UG
About this Product
- SKU:
- ECH-L-9118
- Extra Details:
- XY-17 is a fluorinated phosphonate analog of lysophosphatidic acid (LPA). XY-17 is not hydrolyzed by lipid phosphate phosphatase (LPP) and acts as an agonist of the LPA3 receptor. \n \n \n \nStorage \n-20 °C \n \nAlternate Name: (3S)-1-fluoro-3-hydroxy-4-butyl-1-phosphonate \nFeatured in Publications \n1) Xu, Y., M. Tanaka, et al. (2004). "Alkyl lysophosphatidic acid and fluoromethylene phosphonate analogs as metabolically-stabilized agonists for LPA receptors." Bioorg Med Chem Lett 14(21): 5323-8. \n2) Zhao, Y., P. V. Usatyuk, et al. (2005). "Lipid phosphate phosphatase-1 regulates lysophosphatidic acid-induced calcium release, NF-kappaB activation and interleukin-8 secretion in human bronchial epithelial cells." Biochem. J. 385(2): 493-502. \n3) Prestwich, G., Y. Xu, et al. (2005). "New metabolically stabilized analogues of lysophosphatidic acid: agonists, antagonists and enzyme inhibitors." Biochem Soc Trans 33: 1357-1361. \n4) W.N. Ayre, T. Scott, et al. (2016) "Fluorophosphonate-functionalised titanium via a pre-adsorbed alkane phosphonic acid: a novel dual action surface finish for bone regenerative applications." J Mater Sci Mater Med. Feb;27(2):36. doi: 10.1007/s10856-015-5644-7 \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Echelon Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
