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Microspheres

LPA Beads

Product Sizes
100 ul
£288.00
ECH-L-6101-100UL
1 ml
£1073.00
ECH-L-6101-1ML
About this Product
SKU:
ECH-L-6101
Extra Details:
LPA beads are composed of agarose with 10 nanomoles of bound Lyosphosphatidic Acid (LPA) per mL of beads, enough for several protein binding experiments. Each 1 mL order of LPA Beads includes a small amount of control beads. Larger quantities of Control Beads are also available for purchase. \n \n \n \nStorage \n4 °C - do not freeze \nApplications \nLPA Beads are designed for use in protein pull-down experiments to identify and characterize LPA binding proteins. Possible applications include the isolation of lipid-binding proteins present in a cell lysate or in a mixture of in vitro translated peptides, for separation by SDS-PAGE and further analysis. \nFeatured in Publications \n1) 1. A. S. Nieto-Posadas, G. Picazo-Juaerez, et al. (2012) "Lysophosphatidic acid directly activates TRPV1 through a C-terminal binding site" Nat Chem Biol 8(1), 78-85 doi:10.1038/nchembio.712 \n2) R. Tsukahara, H. Haniu, et al. (2014) "Heart-type fatty-acid-binding protein (FABP3) is a lysophosphatidic acid-binding protein in human coronary artery endothelial cells" FEBS Open Bio 4(1), 947-951 DOI: 10.1016/j.fob.2014.10.014 \n3) S. L. Morales-Lazaro, B. Serrano-Flores, et al. (2014) "Structural Determinants of the Transient Receptor Potential 1 (TRPV1) Channel Activation by Phospholipid Analogs" J. Biol. Chem. 289(35), 24079-24090 10.1074/jbc.M114.572503 \n \nBeing bio-reactive blog: "Lipid-Ligand interaction tools: lipids are not scary intermediates anymore" \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
Shipping Conditions:
Blue Ice
Storage Conditions:
Please refer to datasheet
Supplier:
Echelon Biosciences
Type:
Microspheres: Protein Coated