XY-4 (LPA analog)
Product Sizes
500 ug
£311.00
ECH-L-1160-500UG
About this Product
- SKU:
- ECH-L-1160
- Extra Details:
- (2R)-1,1-difluoro-2-palmitoyloxy-3-phosphopropane (XY-4) is an analog of 2-palmitoyl lysophosphatidic acid (LPA) in which the sn-1 hydroxyl has been replaced by two fluorines. It acts as a selective agonist of peroxisome proliferator-activated receptor G Gamma (PPARG Gamma) but does not stimulate LPA1, LPA2, or LPA3 receptors. PPARG Gamma is a transcription factor of the nuclear receptor superfamily and has been implicated in atherogenesis. \n \n \n \nStorage \n-20 °C \nFeatured in Publications \n1) Zhang, C., D. L. Baker, et al. (2004). "Lysophosphatidic Acid Induces Neointima Formation Through PPARgamma Activation." The Journal of Experimental Medicine 199(6): 763-774. \n2) McIntyre, T. M., A. V. Pontsler, et al. (2003). "Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARgamma agonist." Proceedings of the National Academy of Sciences 100(1): 131-136. \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Echelon Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
