Class III PI3K ELISA Kit
Product Sizes
1 kit
ECH-K-3000-1KIT
About this Product
- SKU:
- ECH-K-3000
- Application:
- ELISA
- Extra Details:
- Echelon's Class III PI3K ELISA Kit is a competitive (96-well) ELISA assay kit that measures Class III Phosphoinositide 3-kinases activity directly through its reaction product, PtdIns(3)P (PI(3)P). \n \n \n \nProduct Background \nThe Class III PI3K ELISA Kit is a competitive ELISA in which the signal is inversely proportional to the amount of PI(3)P produced. After the PI3-K reactions are complete, reaction products are added to the PI(3)P-coated microplate, for competitive binding to a PI(3)P detector protein. The amount of PI(3)P detector protein bound to the plate is determined through colorimetric detection. \nFeatured in Publications \n1. Cao, X., et al. (2009). "Thyroid-hormone-dependent activation of the phosphoinositide 3-kinase/Akt cascade requires Src and enhances neuronal survival." Biochem J 424(2): 201-209. \n2. Mbengue, A., et al. (2015). "A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria." Nature 520: 683-687. \n3. Rajaram, M. V. S., et al. (2017). "M. tuberculosis Initiated Human Mannose Receptor Signaling Regulates Macrophage Recognition and Vesicle Trafficking by FcRg-Chain, Grb2, and SHP-1." Cell Reports 21(1): 126-140. \n4. Su, H., et al. (2017). "VPS34 Acetylation Controls Its Lipid Kinase Activity and the Initiation of Canonical and Non-canonical Autophagy." Mol Cell 67(6): 907-921. \n5. Singla, A., et al. (2019). "Endosomal PI(3)P regulation by the COMMD/CCDC22/CCDC93 (CCC) complex controls membrane protein recycling." Nature Communications 10(1): 4271. \n \nProduct Keywords: PI3K, PI3 Kinase, PI3 K, PI3-K, PI3P \n \n \n \nDocuments \nTechnical Data Sheet \n \nPI3K Assay Comparison Guide, Echelon
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- 2-8[o]C, -20[o]C
- Supplier:
- Echelon Biosciences
- Type:
- Assay Kits: ELISAs
