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Proteins and Peptides

Geranyl Diphosphate (GPP)

Product Sizes
1 mg
£379.00
ECH-I-0100-1MG
10 mg
£939.00
ECH-I-0100-10MG
About this Product
SKU:
ECH-I-0100
Extra Details:
Isoprenoid compounds are a diverse group of natural products which are essential components in all cells. Isoprenoids are biosynthesized from the simple precursors isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Eukaryotes, fungi, and some gram-positive bacteria produce IPP through the mevalonate (MVA) pathway whereas gram-negative and some gram-positive bacteria utilize the non-mevalonate or 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway. \n \n \n \nProvided as the tris-ammonium salt \nFeatured in Publications \n1. Kuzuyama, T., J. P. Noel, et al. (2005). "Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products." Nature 435(7044): 983. \n2. McKay, S. A., W. L. Hunter, et al. (2003). "Insect attack and wounding induce traumatic resin duct development and gene expression of (-)-pinene synthase in Sitka spruce." Plant Physiol 133(1): 368-78. \n3. Schilmiller, A. L., I. Schauvinhold, et al. (2009). "Monoterpenes in the glandular trichomes of tomato are synthesized from a neryl diphosphate precursor rather than geranyl diphosphate." Proceedings of the National Academy of Sciences 106(26): 10865-10870. \n4. Falara, V., Akhtar, T. A., Nguyen, T. T. H., Spyropoulou, E. A., Bleeker, P. M., Schauvinhold, I., ... Pichersky, E. (2011). "The tomato terpene synthase gene family." Plant Physiology, 157(2), 770-789. DOI:10.1104/pp.111.179648 \n5. Blank, P. N., et al. (2017). "Substitution of Aromatic Residues with Polar Residues in the Active Site Pocket of epi-Isozizaene Synthase Leads to the Generation of New Cyclic Sesquiterpenes." Biochemistry 56(43): 5798-5811. \n6. Rea, K. A., et al. (2019). "Biosynthesis of cannflavins A and B from Cannabis sativa L." Phytochemistry 164: 162-171. \n \nAlternate Names: Geranyl pyrophosphate, GPP \n \nBulk discounts available, please email echelon@echelon-inc.com for information. \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
Shipping Conditions:
Blue Ice
Storage Conditions:
Please refer to datasheet
Supplier:
Echelon Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules