Dimethylallyl Diphosphate (DMAPP)
Product Sizes
1 mg
£275.00
ECH-I-0051-1MG
10 mg
£830.00
ECH-I-0051-10MG
About this Product
- SKU:
- ECH-I-0051
- Extra Details:
- Isoprenoid compounds are a diverse group of natural products which are essential components in all cells. Isoprenoids are biosynthesized from the simple precursors isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Eukaryotes, fungi, and some gram-positive bacteria produce IPP through the mevalonate (MVA) pathway whereas gram-negative and some gram-positive bacteria utilize the non-mevalonate or 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway. \n \n \n \nProvided as the tris-ammonium salt \nFeatured in Publications \n1. Burke, C. and R. Croteau (2002). "Interaction with the small subunit of geranyl diphosphate synthase modifies the chain length specificity of geranylgeranyl diphosphate synthase to produce geranyl diphosphate." J Biol Chem 277(5): 3141-9. \n2. Poliquin, K., Y. V. Ershov, et al. (2004). "Inactivation of sll1556 in Synechocystis Strain PCC 6803 Impairs Isoprenoid Biosynthesis from Pentose Phosphate Cycle Substrates In Vitro." J Bacteriol 186(14): 4685-4693. \n3. Schilmiller, A. L., I. Schauvinhold, et al. (2009). "Monoterpenes in the glandular trichomes of tomato are synthesized from a neryl diphosphate precursor rather than geranyl diphosphate." Proceedings of the National Academy of Sciences 106(26): 10865-10870. \n4. Haymond, A., et al. (2014). "Kinetic Characterization and Allosteric Inhibition of the Yersinia pestis 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase (MEP Synthase)." PLoS ONE 9(8): e106243. \n5. Gruenbacher, G., et al. (2016). "Ecto-ATPase CD39 Inactivates Isoprenoid-Derived VG Gamma9VD Delta2 T Cell Phosphoantigens." Cell Reports 16(2): 444-456. \n6. Ma, Y., et al. (2019). "Metabolic Engineering of the MEP Pathway in Bacillus subtilis for Increased Biosynthesis of Menaquinone-7." ACS Synthetic Biology 8(7): 1620-1630. \n \nAlternate Names: Dimethylallyl pyrophosphate, DMPP \n \nBulk discounts available, please email echelon@echelon-inc.com for information. \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Echelon Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
