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Proteins and Peptides

Isopentenyl Diphosphate (IPP)

Product Sizes
1 mg
£379.00
ECH-I-0050-1MG
10 mg
£814.00
ECH-I-0050-10MG
About this Product
SKU:
ECH-I-0050
Extra Details:
Isoprenoid compounds are a diverse group of natural products which are essential components in all cells. Isoprenoids are biosynthesized from the simple precursors isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Eukaryotes, fungi, and some gram-positive bacteria produce IPP through the mevalonate (MVA) pathway whereas gram-negative and some gram-positive bacteria utilize the non-mevalonate or 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway. \n \n \n \nProvided as the tris-ammonium salt \nFeatured in Publications \n1. Wouters, J., Y. Oudjama, et al. (2003). "Structure and mechanism of action of isopentenylpyrophosphate- dimethylallylpyrophosphate isomerase." J Am Chem Soc 125(11): 3198-9. \n2. Schilmiller, A. L., I. Schauvinhold, et al. (2009). "Monoterpenes in the glandular trichomes of tomato are synthesized from a neryl diphosphate precursor rather than geranyl diphosphate." Proceedings of the National Academy of Sciences 106(26): 10865-10870. \n3. Bang, S., S. Yoo, et al. (2010). "Farnesyl pyrophosphate is a novel pain-producing molecule via specific activation of TRPV3." J Biol Chem 285(25): 19362-71. \n4. Haymond, A., et al. (2014). "Kinetic Characterization and Allosteric Inhibition of the Yersinia pestis 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase (MEP Synthase)." PLoS ONE 9(8): e106243. \n5. Wang, X., et al. (2018). "MEPicides: A Alpha,B Beta-Unsaturated Fosmidomycin Analogs as DXR inhibitors against Malaria." J Med Chem 61(19): 8847-8858. \n6. Rea, K. A., et al. (2019). "Biosynthesis of cannflavins A and B from Cannabis sativa L." Phytochemistry 164: 162-171. \n \nAlternate Names: Isopentenyl pyrophosphate, IPP \n \nBulk discounts available, please email echelon@echelon-inc.com for information. \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
Shipping Conditions:
Blue Ice
Storage Conditions:
Please refer to datasheet
Supplier:
Echelon Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules