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Proteins and Peptides

BODIPY FL PI(3)P

Product Sizes
50 ug
£868.00
ECH-C-03F6-50UG
100 ug
£1352.00
ECH-C-03F6-100UG
About this Product
SKU:
ECH-C-03F6
Extra Details:
BODIPY FL PI(3)P (BODIPY FL Phosphatidylinositol 3-phosphate) is a water soluble analog of PI(3)P labeled with the green fluorophore, Bodipy®-FL at the sn-1 position. \n \n \n \nPhosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3-phosphate is enriched in early endosomes having roles in endosome fusion and receptor sorting and internalization in multivesicular bodies. PI(3)P has also been found at the plasma membrane and is involved in the translocation of the glucose transport protein GLUT4. \nExcitation/Emission \n503/513 nm \nStorage \n-20 °C, protect from light \nFeatured in Publications \n1) Caromile, L. A., A. Oganesian, et al. (2010). "The neurosecretory vesicle protein phogrin functions as a phosphatidylinositol phosphatase to regulate insulin secretion." J Biol Chem 285(14): 10487-96. \n2)Rudge, S. A., D. M. Anderson, et al. (2004). "Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase." Mol Biol Cell 15(1): 24-36. \n3) Oganesian, A., M. Poot, et al. (2003). "Protein tyrosine phosphatase RQ is a phosphatidylinositol phosphatase that can regulate cell survival and proliferation." Proc Natl Acad Sci U S A 100(13): 7563-8. \n \nBulk discounts available, please email echelon@echelon-inc.com for information. \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
Shipping Conditions:
Dry Ice
Storage Conditions:
Please refer to datasheet
Supplier:
Echelon Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules