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Proteins and Peptides

AS1938909 (SHIP2 Inhibitor)

Product Sizes
5 mg
£215.00
ECH-B-0343-5MG
10 mg
£333.00
ECH-B-0343-10MG
25 mg
£653.00
ECH-B-0343-25MG
About this Product
SKU:
ECH-B-0343
Extra Details:
AS1938909 is a potent SHIP2 inhibitor (Ki = 0.44uM). This compound shows signficant selectivity over some related phosphatases (IC50 = 0.18uM, 21uM, >50uM for mSHIP2, hSHIP2, hPTEN respectively). It also enhances Akt phosphorylation and increases glucose consumption and uptake in L6 myotubes. \n \n \n \nStorage \n2-8 °C \nReferences \nA Suwa, T Yamanoto et al. "Glucose metabolism activation by SHIP2 inhibitors via up-regulation of GLUT1 gene in L6 myotubes" Eur J Pharmaco, 2010, 642, 177 \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
Shipping Conditions:
Ambient
Storage Conditions:
Please refer to datasheet
Supplier:
Echelon Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors