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Proteins and Peptides

AS1949490 (SHIP2 Inhibitor)

Product Sizes
5 mg
£209.00
ECH-B-0342-5MG
10 mg
£323.00
ECH-B-0342-10MG
25 mg
£653.00
ECH-B-0342-25MG
About this Product
SKU:
ECH-B-0342
Extra Details:
AS1949490 is a potent, selective SHIP2 inhibitor with IC50 of 0.62 uM for human, which shows less effect on SHIP1 or no effects on some other types of intracellular phosphatases (such as PTEN, synaptojanin, and myotubularin). This compound also activates intracellular insulin signaling pathways in the liver and displays gluconeogensis regulation and antidiabetic effects. \n \n \n \nStorage \n2-8 °C \nReferences \nA. Suwa, T. Yamanoto, et al. "Discovery and functional characterization of a novel small molecule inhibitor of the intracellular phosphatase, SHIP2", British Journal of Pharmacology, 2009,158, 879-88. \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
Shipping Conditions:
Ambient
Storage Conditions:
Please refer to datasheet
Supplier:
Echelon Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors