IC87114 (PI3-K delta inhibitor)
Product Sizes
1 mg
£132.00
ECH-B-0305-1MG
5 mg
£203.00
ECH-B-0305-5MG
25 mg
£594.00
ECH-B-0305-25MG
About this Product
- SKU:
- ECH-B-0305
- Extra Details:
- IC87114 is a specific inhibitor of PI 3-kinase D Delta (IC50 = 0.5 uM) with >60-fold selectivity over other isoforms (IC50: A Alpha = >100 uM, B Beta = 75 uM, G Gamma = 29 uM). It does not inhibit other protein kinases (p38MAPK, CHK1, cSrc, PKBA Alpha, CK1, PKCA Alpha, PKCB BetaII) at 10 uM. PI 3-K &delta has an important role in inflammation and inhibition has been shown to impair neutrophil migration. Administration of IC87114 in a mouse asthma model decreased allergic airway inflammation. \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Echelon Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
