AS604850 (PI3-K gamma Inhibitor 2)
Product Sizes
1 mg
£119.00
ECH-B-0302-1MG
5 mg
£228.00
ECH-B-0302-5MG
About this Product
- SKU:
- ECH-B-0302
- Extra Details:
- 5-(2,2-Difluoro-benzo[1,3]dioxol-5-ylmethylene)-thiazolidine-2,4-dione (AS604850) is an inhibitor of PI 3-KG Gamma with an IC50 = 250 nM. AS604850 is selective for the G Gamma-isoform (IC50: PI 3-KA Alpha = 4.5 uM, PI 3-KB Beta, PI 3-KD Delta > 20 uM) and shows no notable activity against a wide array of protein kinases at 1 uM. \n \n \n \nSolubility \nWater: insoluble, DMSO: 5 mg/mL \nStorage \nStore dry between 2-8oC. Stock solutions should be stored frozen (-20oC). \nReferences \n1) M. Camps et al. "Blockade of PI3Kg suppresses joint inflammation and damage in mouse models of rheumatoid arthritis" Nature Medicine, 2005, 11, 936-943. \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Echelon Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
