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Proteins and Peptides

CYM50308 (S1P4 Receptor Agonist)

Product Sizes
10 mg
£275.00
ECH-B-0060-10MG
25 mg
£547.00
ECH-B-0060-25MG
50 mg
£897.00
ECH-B-0060-50MG
About this Product
SKU:
ECH-B-0060
Extra Details:
CYM50308 is a potent and selective S1P4 receptor agonist with EC50 of 37.7 nM - 79.1nM. It is inactive against the S1P1, S1P2, and S1P3 receptors up to 25 uM, and the S1P5 receptor up to 2.1 uM. \n \n \n \nStorage \n4 °C \nReferences \n1) Urbano et al. Discovery, synthesis and SAR analysis of novel selective small molecule S1P4-R agonists based on a (2Z,5Z)-5-((pyrrol-3-yl)methylene)-3-alkyl-2- (alkylimino)thiazolidin-4-one chemotype, Bioorganic & Medicinal Chemistry Letters, 2011, 6739-6745. \n2) Guerrero et al. Identification of a novel agonist of the sphingosine 1-phosphate receptor 4 (S1P4), Probe Reports from the NIH Molecular Libraries Program. http://www.ncbi.nlm.nih.gov/books/NBK143556/ \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
Shipping Conditions:
Ambient
Storage Conditions:
Please refer to datasheet
Supplier:
Echelon Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules