Sphingosine Kinase Inhibitor (SKI-II)
Product Sizes
10 mg
£167.00
ECH-B-0024-10MG
50 mg
£448.00
ECH-B-0024-50MG
About this Product
- SKU:
- ECH-B-0024
- Extra Details:
- 2-(p-Hydroxyanilino)-4-(p-chlorophenyl)thiazole (SK1-II) is a cell permeable, potent, and specific inhibitor of sphingosine kinase (IC50 = 0.5 uM). The compound does not bind to the ATP-binding site and does not affect the kinase activities of hERK2, hPI3K, or hPKCA Alpha at concentrations up to 60 uM. SK1-II showed anti-tumor properties, inducing apoptosis in a number of cell lines including those that express Pgp or MRP1 drug-transport proteins. \n \n \n \nSolubility \nDMSO, >5 mg/mL \n \n \n \nDocuments \n \n \n \nTechnical Data Sheet, Echelon
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Echelon Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
