Extracellular Death Factor

Product Sizes

1 mg

£295.00

ECH-950-10-1MG

About this Product

SKU:: ECH-950-10
CAS Number:: 960129-66-2
Extra Details:: CAS Number: 960129-66-2 \nMolecular Weight: 660 \nSalt Form: TFA \nPurity: >95% \nSequence (3-letter): Asn-Asn-Trp-Asn-Asn-OH \nSequence (1-letter): NNWNN-OH \nStorage: -20 ?C or below \n \nExtracellular death factor (EDF) is a linear pentapeptide that activates the cell death pathway in a subset of communicating cells. Programmed cell death in bacteria is dependent on a system of cell-to-cell communication termed quorum sensing. It is sensitive to extreme pH, high temperatures, and other cellular stress. EDF has been shown to trigger cell death at 2.5 ng/ml which significantly reduces population size in some E. coli cultures. \nReferences \nBelitsky M, Avshalom H, Erental A, Yelin I, Kumar S, London N, Sperber M, Schueler-Furman O, Engelberg-Kulka H (2011) "The Escherichia coli Extracellular Death Factor EDF Induces the Endoribonucleolytic Activities of the Toxins MazF and ChpBK" Mol. Cell 41 (6) 625-635, Echelon
Molecular Weight:: 660
Sequence:: Asn-Asn-Trp-Asn-Asn-OH \n
Shipping Conditions:: Ambient
Storage Conditions:: -20[o]C
Supplier:: Echelon Biosciences
Type:: Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides

Basket